[HTML][HTML] Nanoparticles modified with cell-penetrating peptides: Conjugation mechanisms, physicochemical properties, and application in cancer diagnosis and …

I Gessner, I Neundorf - International journal of molecular sciences, 2020 - mdpi.com
… versatile vehicles for the intracellular transport of various cargos, … On the other hand,
endocytosis is mainly observed when larger … fate of conjugates in comparison to their individual …

Macropinocytosis as a cell entry route for peptide-functionalized and bystander nanoparticles

YX Li, HB Pang - Journal of controlled release, 2021 - Elsevier
Endocytic pathways provide the primary route for therapeutic … cell-penetrating peptides
(CPPs), a family of short peptides (… enables the conjugates to access their intracellular targets, …

[HTML][HTML] Internalization mechanisms of cell-penetrating peptides

I Ruseska, A Zimmer - Beilstein journal of nanotechnology, 2020 - beilstein-journals.org
Endocytosis as a mechanism for the transport of CPPs … conjugated to nanoparticles and
perhaps macromolecules. … The future fate of these structures is not entirely clear. Viruses are …

[HTML][HTML] Cell-Penetrating and Targeted Peptides Delivery Systems as Potential Pharmaceutical Carriers for Enhanced Delivery across the Blood–Brain Barrier (BBB)

SM Ghorai, A Deep, D Magoo, C Gupta, N Gupta - Pharmaceutics, 2023 - mdpi.com
… shuttles, and brain-permeable peptide–drug conjugates (PDCs… TAT-peptides conjugated to
iron oxide nanoparticles were the … endocytosis (CME), the interaction of peptides with specific …

Cell-penetrating peptides (CPPs): An overview of applications for improving the potential of nanotherapeutics

K Desale, K Kuche, S Jain - Biomaterials Science, 2021 - pubs.rsc.org
… with CPPs conjugated with nanoparticles over HSPG. … in the areas such as intracellular
transport of siRNAs, nucleotides, … receptor-mediated endocytosis. For example, a cyclic RGD …

Cell-Penetrating Peptides as Keys to Endosomal Escape and Intracellular Trafficking in Nanomedicine Delivery

S Soni, SK Kori, P Nema, AK Iyer… - Current Medicinal …, 2024 - ingentaconnect.com
… effectual intracellular transport of nanoparticles within cells … ceptor-mediated endocytosis,
and delivery vectors based on … release of cationic peptide-conjugated peptide nucleic acids …

[HTML][HTML] An update on cell-penetrating peptides with intracellular organelle targeting

CP Cerrato, Ü Langel - Expert Opinion on Drug Delivery, 2022 - Taylor & Francis
… associate with cells and whether particles were internalized in an endocytic or nonendocytic
… TAT peptide has been conjugated on the surface of mesoporous organosilica nanoparticles

Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives

AFL Schneider, M Kithil, MC Cardoso, M Lehmann… - Nature Chemistry, 2021 - nature.com
… uptake of protein–CPP conjugates in a non-endocytic mode, even at … conjugation of a single
TAT peptide can be used to transport … Our future work will be directed at making use of this …

Cell-penetrating peptides delivering siRNAs: an overview

L Falato, M Gestin, Ü Langel - Design and Delivery of SiRNA Therapeutics, 2021 - Springer
… 7]) and CPP-based nanoparticles capable of higher specificity … , are, in some cases,
conjugated covalently to the siRNA to … The complexes were able to enter the cells via endocytic

[HTML][HTML] Delivery of various cargos into cancer cells and tissues via cell-penetrating peptides: A review of the last decade

A Shoari, R Tooyserkani, M Tahmasebi, DWPM Löwik - Pharmaceutics, 2021 - mdpi.com
… viral-based vectors, nanoparticles and cell-penetrating peptides (… that the conjugation
between CPPs and nanoparticles is a … co-localization in different endocytic vesicles is probable. …